East Tennessee Children's Hospital Installs Masimo Patient SafetyNet System for Improved Oversight of Postoperative Patients

April 5, 2013
Installation Is Part of the Organization-Wide Conversion to Masimo SET® Pulse Oximetry and Use of rainbow® Pulse CO-Oximetry™ for Advanced Patient Monitoring

KNOXVILLE, Tenn. and IRVINE, Calif., April 5, 2013 /PRNewswire via COMTEX/ -- East Tennessee Children's Hospital, one of four hospitals in Tennessee to be certified as a Comprehensive Regional Pediatric Center, and Masimo (NASDAQ: MASI) today announced that the hospital has deployed Masimo Patient SafetyNet™, clinically shown to help improve patient outcomes and save money.1

The installation at East Tennessee Children's is part of the leading pediatric healthcare organization's standardization to Masimo SET® Measure-Through Motion and Low Perfusion pulse oximetry and rainbow® Pulse CO-Oximetry.

"We are excited about the extra layer of safety for our postoperative patients for inpatient surgery," said Debi Dobbs, Nurse Manager at East Tennessee Children's Hospital. "It's especially beneficial for those patients who suffer from respiratory depression, and we are exploring placing the Patient SafetyNet system in additional units."

East Tennessee Children's joins a growing list of prominent health systems using Patient SafetyNet, which can help ensure patients' safety by noninvasively and continuously measuring and tracking their underlying physiological conditions and detect changes or abnormalities that signal declining health status in real-time. When changes occur in the measured values, which may indicate deterioration in the patient's condition, the system automatically sends wireless alerts directly to clinicians – prompting a potentially lifesaving response to the patient's bedside. Patient SafetyNet also has been clinically shown to reduce preventable and costly rescue events and transfers to intensive care units.1

In addition, East Tennessee Children's Hospital patients will benefit from breakthrough rainbow® technology that allows clinicians to noninvasively measure multiple blood constituents, respiration rate, and other physiological parameters. Parameters in use at East Tennessee Children's include total hemoglobin (SpHb®) in operating rooms, in addition to the Measure-Through Motion and Low Perfusion performance of Masimo SET® oxyhemoglobin (SpO2), perfusion index (PI), and pulse rate (PR). The pulse oximetry standard-of-care at leading hospitals worldwide, Masimo SET® virtually eliminates false alarms2 and increases a clinician's ability to detect life-threatening events.3

Masimo's SpHb enables clinicians to monitor hemoglobin and trending noninvasively and continuously,4 and has been clinically shown to help anesthesiologists reduce the frequency of unnecessary blood transfusions,5 which carry risks that include a significant link to mortality and infection.6

"There is no higher calling in medicine than to offer the best care possible for children, and East Tennessee Children's Hospital has shown that caring for children is its top concern," said Joe Kiani, founder and CEO of Masimo. "We are delighted to be partnering with East Tennessee Children's Hospital to help protect young patients, improve outcomes, and reduce costs."

1 Taenzer A, Blike G, McGrath S, Pyke J, Herrick M, Renaud C, Morgan J. "Postoperative Monitoring – The Dartmouth Experience." Anesthesia Patient Safety Foundation Newsletter Spring-Summer 2012. Available online 2 Shah N, Ragaswamy H, Govindugari K, Estanol L. "Performance of three new-generation pulse oximeters during motion and low perfusion in volunteers." Journal of Clinical Anesthesia. 2012 (10.1016/j.jclinane.2011.10.012) Available online here 3 Taenzer, Andreas H.; Pyke, Joshua B.; McGrath, Susan P.; Blike, George T. "Impact of Pulse Oximetry Surveillance on Rescue Events and Intensive Care Unit Transfers: A Before-and-After Concurrence Study." Anesthesiology, February 2010, Vol. 112, Issue 2. Available online here 4 Frasca D., Dahyot-Fizelier C., Catherine K., Levrat Q., Debaene B., Mimoz O. "Accuracy of a Continuous Noninvasive Hemoglobin Monitor in Intensive Care Unit Patients." Crit Care Med. 2011 Oct;39(10):2277-82. Available online here. 5Ehrenfeld JM, Henneman JP, Sandberg WS. "Impact of Continuous and Noninvasive Hemoglobin Monitoring on Intraoperative Blood Transfusions." American Society Anesthesiologists. 2010;LB05 6 Marik, P. E. and H. L. Corwin (2008). "Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature." Crit Care Med 36(9): 2667-74.

About East Tennessee Children's Hospital
As a Comprehensive Regional Pediatric Center, East Tennessee Children's Hospital offers full capabilities to care for seriously ill children in a unique pediatric environment separated from adult care areas, as well as offering the services of many different pediatric subspecialties. East Tennessee Children's Hospital works jointly with the University of Tennessee Medical Center to ensure that injured children in this region receive trauma care at the institution most appropriate for the child's needs. Comprehensive centers also are responsible for assisting smaller hospitals to meet the requirements of their selected designations, primarily by providing pediatric health care training opportunities to these hospitals. East Tennessee Children's Hospital was the first hospital in East Tennessee to be certified by the state as a Comprehensive Regional Pediatric Center. For more information, please visit http://www.etch.com/homepage.aspx

About Masimo
Masimo (NASDAQ: MASI) is the global leader in innovative noninvasive monitoring technologies that significantly improve patient care—helping solve "unsolvable" problems. In 1995, the company debuted Measure-Through Motion and Low Perfusion pulse oximetry, known as Masimo SET®, which virtually eliminated false alarms and increased pulse oximetry's ability to help clinicians detect life-threatening events. More than 100 independent and objective studies have shown that Masimo SET® outperforms other pulse oximetry technologies, even under the most challenging clinical conditions, including patient motion and low peripheral perfusion. In 2005, Masimo introduced rainbow ® Pulse CO-Oximetry™ technology, allowing noninvasive and continuous monitoring of blood constituents that previously required invasive procedures; total hemoglobin (SpHb®), oxygen content (SpOC), carboxyhemoglobin (SpCO®), methemoglobin (SpMet®), PVI®, and perfusion index (PI), in addition to measure-through motion SpO2, and pulse rate. In 2008, Masimo introduced Patient SafetyNet™, a remote monitoring and wireless clinician notification system designed to help hospitals avoid preventable deaths and injuries associated with failure to rescue events. In 2009, Masimo introduced rainbow® Acoustic Monitoring, the first-ever commercially available noninvasive and continuous monitoring of acoustic respiration rate (RRa™). Masimo SET® and Masimo rainbow® technologies also can be found in over 100 multiparameter patient monitors from over 50 medical device manufacturers around the world. Founded in 1989, Masimo has the mission of "Improving Patient Outcome and Reducing Cost of Care … by Taking Noninvasive Monitoring to New Sites and Applications®." Additional information about Masimo and its products may be found at www.masimo.com.

Forward Looking Statements
This press release includes forward-looking statements as defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, in connection with the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on current expectations about future events affecting us and are subject to risks and uncertainties, all of which are difficult to predict and many of which are beyond our control and could cause our actual results to differ materially and adversely from those expressed in our forward-looking statements as a result of various risk factors, including, but not limited to: risks related to our assumptions that the hospital-wide conversion ensures that all East Tennessee Children's patients will be cared for using the most technologically and clinically advanced noninvasive patient monitoring solutions available; risks related to our belief that Masimo Patient SafetyNet can help keep patients safer by noninvasively, continuously measuring and tracking their underlying physiological condition to help hospitals avoid preventable patient deaths and injuries associated with failure to rescue events, risks related to our assumptions of the repeatability of clinical results obtained, and risks related to the system's ability to significantly decrease traumatic critical events and costly ICU transfers to help improve patient outcomes and reduce costs; risks related to our belief that SpHb helps clinicians measure hemoglobin and trending noninvasively and continuously, and reduces the frequency of unnecessary blood transfusions; risks related to our believe Masimo SET virtually eliminates false alarms and increases a clinician's ability to detect life-threatening events; as well as other factors discussed in the "Risk Factors" section of our most recent reports filed with the Securities and Exchange Commission ("SEC"), which may be obtained for free at the SEC's website at www.sec.gov. Although we believe that the expectations reflected in our forward-looking statements are reasonable, we do not know whether our expectations will prove correct. All forward-looking statements included in this press release are expressly qualified in their entirety by the foregoing cautionary statements. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of today's date. We do not undertake any obligation to update, amend or clarify these forward-looking statements or the "Risk Factors" contained in our most recent reports filed with the SEC, whether as a result of new information, future events or otherwise, except as may be required under the applicable securities laws.

Media Contact:

Erica Estep

Mike Drummond

East Tennessee Children's Hospital

Masimo Corporation

Phone: (865) 541-8276

Phone: (949) 297-7434

Email: ESEstep@etch.com

Email: mdrummond@masimo.com

Masimo, SET, Signal Extraction Technology, Improving Patient Outcome and Reducing Cost of Care... by Taking Noninvasive Monitoring to New Sites and Applications, rainbow, SpHb, SpOC, SpCO, SpMet, PVI, rainbow Acoustic Monitoring, RRa, Radical-7, Rad-87, Rad-57,Rad-8, Rad-5,Pulse CO-Oximetry, Pulse CO-Oximeter, Adaptive Threshold Alarm, and SedLine are trademarks or registered trademarks of Masimo Corporation. The use of the trademarks Patient SafetyNet and PSN is under license from University HealthSystem Consortium.